mapk erk pathway activator ro 67 7476 Search Results


ro 67 7476  (MedChemExpress)
95
MedChemExpress ro 67 7476
Fig. 6. ARC@DPBNs attenuated macrophage pyroptosis and M1 polarization partly by inhibiting ERK pathway. RAW264.7 cells were treated with PBS, 1 μg/ mLLPS, 1 μg/mL LPS and 0.5 μM. ARC@DPBNPs with or without 150 nM <t>Ro</t> <t>67–7476</t> for 24 h. (A-D) Western blotting images and quantifications of GSDMD, Caspase-1/4/11, NLRP3, p-ERK and ASC. (E) Immuno-fluorescent staining analysis of ASC. (F and G) The contents of F4/80+CD86+ and F4/80+CD206+ RAW264.7 cells were detected by flow cytometry. Data were expressed as mean ± SD, n = 3 per group. **P < 0.01 vs. NC, #P < 0.05, ##P < 0.01 vs. LPS, $XXX$P < 0.01 vs. LPS + ARC@DPBNPs.
Ro 67 7476, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mapk+erk+pathway+activator+ro+67+7476/Ro+67-7476/pm38457983-64-0-9
Average 95 stars, based on 1 article reviews
ro 67 7476 - by Bioz Stars, 2026-09
95/100 stars
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ro 67-7476  (Bio-Techne corporation)
89
Bio-Techne corporation ro 67-7476
Fig. 6. ARC@DPBNs attenuated macrophage pyroptosis and M1 polarization partly by inhibiting ERK pathway. RAW264.7 cells were treated with PBS, 1 μg/ mLLPS, 1 μg/mL LPS and 0.5 μM. ARC@DPBNPs with or without 150 nM <t>Ro</t> <t>67–7476</t> for 24 h. (A-D) Western blotting images and quantifications of GSDMD, Caspase-1/4/11, NLRP3, p-ERK and ASC. (E) Immuno-fluorescent staining analysis of ASC. (F and G) The contents of F4/80+CD86+ and F4/80+CD206+ RAW264.7 cells were detected by flow cytometry. Data were expressed as mean ± SD, n = 3 per group. **P < 0.01 vs. NC, #P < 0.05, ##P < 0.01 vs. LPS, $XXX$P < 0.01 vs. LPS + ARC@DPBNPs.
Ro 67 7476, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 89/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mapk+erk+pathway+activator+ro+67+7476/Ro+67-7476/custom%404346%4036427324
Average 89 stars, based on 1 article reviews
ro 67-7476 - by Bioz Stars, 2026-09
89/100 stars
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cyp4f22 antibody - middle region (arp67476_p050)  (Aviva Systems)
N/A
This is a rabbit polyclonal antibody against CYP4F22. It was validated on Western Blot by Aviva Systems Biology. At Aviva Systems Biology we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high
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ro 67 7476  (Cayman Chemical)
N/A
Ro 67 7476 is a positive allosteric modulator of metabotropic glutamate receptor 1 mGluR1 that enhances glutamate induced calcium release in HEK293 cells expressing rat mGluR1a EC 1 74 μM It is selective for rat
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cyp4f22 peptide - middle region (aap67476)  (Aviva Systems)
N/A
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krt7 polyclonal antibody  (Elabscience Biotechnology)
N/A
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during
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3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid-13c4 ethyl ester  (Toronto Research Chemicals)
N/A
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gm 6001  (Aladdin Scientific Corporation)
N/A
Application:(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide has been used: To study its effect on the profiling of active aggrecanases and their specific aggrecan degradation fragments. To study the involvement of autocrine EGF (epidermal growth factor) receptor activation in the regulation
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ro 67-7476  (TargetMol)
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carbasalate calcium  (MedChemExpress)
N/A
Carbasalate calcium is an anti-inflammatory, antipyretic, and analgesic agent.
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Image Search Results


Fig. 6. ARC@DPBNs attenuated macrophage pyroptosis and M1 polarization partly by inhibiting ERK pathway. RAW264.7 cells were treated with PBS, 1 μg/ mLLPS, 1 μg/mL LPS and 0.5 μM. ARC@DPBNPs with or without 150 nM Ro 67–7476 for 24 h. (A-D) Western blotting images and quantifications of GSDMD, Caspase-1/4/11, NLRP3, p-ERK and ASC. (E) Immuno-fluorescent staining analysis of ASC. (F and G) The contents of F4/80+CD86+ and F4/80+CD206+ RAW264.7 cells were detected by flow cytometry. Data were expressed as mean ± SD, n = 3 per group. **P < 0.01 vs. NC, #P < 0.05, ##P < 0.01 vs. LPS, $XXX$P < 0.01 vs. LPS + ARC@DPBNPs.

Journal: International immunopharmacology

Article Title: ARC@DPBNPs suppress LPS-induced acute lung injury via inhibiting macrophage pyroptosis and M1 polarization by ERK pathway in mice.

doi: 10.1016/j.intimp.2024.111794

Figure Lengend Snippet: Fig. 6. ARC@DPBNs attenuated macrophage pyroptosis and M1 polarization partly by inhibiting ERK pathway. RAW264.7 cells were treated with PBS, 1 μg/ mLLPS, 1 μg/mL LPS and 0.5 μM. ARC@DPBNPs with or without 150 nM Ro 67–7476 for 24 h. (A-D) Western blotting images and quantifications of GSDMD, Caspase-1/4/11, NLRP3, p-ERK and ASC. (E) Immuno-fluorescent staining analysis of ASC. (F and G) The contents of F4/80+CD86+ and F4/80+CD206+ RAW264.7 cells were detected by flow cytometry. Data were expressed as mean ± SD, n = 3 per group. **P < 0.01 vs. NC, #P < 0.05, ##P < 0.01 vs. LPS, $XXX$P < 0.01 vs. LPS + ARC@DPBNPs.

Article Snippet: RO 67–7476 (an activator of ERK) was purchased from MCE (cat# HY100403, Shanghai, China).

Techniques: Western Blot, Staining, Flow Cytometry